https://drgailhumble.com/

In this episode, Christian Drapeau interviews Dr. Gail Humble, who delves into her work with the Klotho gene, the only known longevity gene, which has shown remarkable results in extending lifespan and maintaining cellular youthfulness. Discovered in 1997, the Klotho gene blocks oxidative stress, helping cells to remain functional for up to 30% longer. Dr. Humble explains how this gene, which exists in all mammals, can slow the aging process when its protein is applied to skin cells, significantly reducing DNA damage and reversing photo-aging by about 40%.

Dr. Humble also highlights the research being conducted on the Klotho protein’s ability to reverse cognitive decline in Alzheimer’s models, demonstrating its far-reaching potential beyond skincare. The discussion touches on the mechanisms by which the protein enhances cellular health, including its impact on oxidative stress and the activation of key enzymes such as superoxide dismutase (SOD).

This episode offers an in-depth look into how genetic research and topical applications of the Klotho protein could redefine anti-aging treatments and contribute to the future of longevity medicine. Dr. Humble’s insights open the door to new possibilities in both aesthetic and cognitive health, offering hope for slowing the progression of age-related diseases.