Conversations Unplugged
with Dave Pascoe
Join STEMREGEN Founder and Chief Science Officer Christian Drapeau as he sits down with world-ranked biohacker Dave Pascoe, a top contender in the Rejuvenation Olympics and a passionate self-experimenter. In this fascinating conversation, Dave shares his meticulous approach to tracking aging markers, the secrets behind staying biologically young, and how exercise, food, and sleep each play a pivotal role in longevity. With data from hundreds of personal tests and a dedication to open-source biohacking, Dave opens up about what’s working—and what’s not. This episode is a deep dive into the future of health tracking, stem cell activation, and how lifestyle choices can reverse your biological clock.
Dave Pascoe
Dave Pascoe isn’t just another health enthusiast—he’s one of the top-ranked individuals in the Rejuvenation Olympics, a global leaderboard of biological youth. He tests his blood monthly, tracks DNA methylation, logs hormone levels quarterly, and builds graphs to monitor his markers against youthful baselines. But what sets Dave apart is his relentless experimentation: he’s tested himself at both his peak and his worst, all to better understand how various inputs—diet, exercise, environment—shift his pace of aging. His insights are data-driven, honest, and deeply personal.
In his conversation with Christian, Dave shares how seasonal changes, stress, and even subtle light exposure affect his sleep and performance. He discusses how summer outdoor activity boosts his biological metrics, while winter slows things down. His non-negotiables? Clean, unprocessed food, consistent movement, and quality sleep—three pillars of optimal health echoed across the Rejuvenation Olympics leaderboard. And when it comes to sleep, Dave swears by blackout curtains and sleep masks, reminding us that the smallest environmental tweaks can have a major impact on rest and recovery.
Christian and Dave also touch on the fascinating topic of stem cell release and its relationship to mechanical stimulation. From trampoline workouts to vibration plates and running, they explore how physical impact on bone marrow—especially in the pelvis and rib cage—may help stimulate natural stem cell release. The discussion ties back to Christian’s ongoing clinical research with STEMREGEN, where early trials in heart failure and Parkinson’s disease are showing remarkable results simply by enhancing the body’s innate repair system.
Finally, the episode closes on the topic of habit transformation and Christian’s passion project: the 60-Day Challenge. Designed to help individuals shift deeply ingrained behaviors, this program targets not just physical health but mental, emotional, and spiritual well-being. Dave enthusiastically supports the concept and pledges to revisit the challenge himself. Together, Dave and Christian agree—if stem cells can rebuild the body, intentional habits can rebuild the self.