Conversations Unplugged
with Melanie Avalon
Join STEMREGEN Founder and Chief Science Officer Christian Drapeau as he sits down with Melanie Avalon, actress, author, and host of the wildly popular Melanie Avalon Biohacking Podcast. In this engaging conversation, Melanie and Christian explore the current state of stem cell science, how it's finally entering mainstream acceptance, and how it may redefine how we understand aging, healthspan, and the body’s innate repair system. Christian also gives a sneak peek into his upcoming book and shares what he believes could be the most important biomarker of aging yet—your circulating stem cell count.
Melanie Avalon
In this high-energy, forward-looking conversation, Melanie Avalon and Christian Drapeau unpack a growing paradigm shift in the way we understand aging—not as something fixed or chronological, but as something potentially measurable and even modifiable. As Christian explains, stem cells play a central role in the body's innate repair system. For decades, he faced skepticism and pushback for saying that adult stem cells could become cells of other tissues. But today, there's a new openness, and the science is finally catching up.
Christian discusses the evolution from his first book, Cracking the Stem Cell Code, to the second book he's currently working on. The goal of the new book is to take highly technical, scientifically dense information and translate it into a clear, accessible narrative anyone can understand—essentially telling the story of how stem cells shape the future of health. And one major idea he's introducing: stem cells as a measurable healthspan biomarker. If you have too few circulating stem cells, you may be on track to develop specific health challenges—even if you feel fine today.
Melanie, known for her deep dives into longevity science, brings up the rise of biological age tests. Christian highlights the limitations of current methods like DNA methylation, which can fluctuate wildly under stress. Instead, he proposes a more concrete approach: identifying a threshold of stem cells in the bloodstream that indicates whether your body is maintaining itself efficiently. This shift could change how we track health over time, moving us toward truly preventative and personalized care.
This episode closes with excitement for what's next: new technologies to make stem cell testing affordable and accessible, and deeper conversations around how lifestyle, supplementation, and stress impact your stem cell levels. If you care about aging well, maximizing your body's repair potential, and staying ahead of the curve in health science, this is an episode you won't want to miss.