Conversations Unplugged
with Ulrich Dempfle
Join STEMREGEN Founder and Chief Science Officer Christian Drapeau in a dynamic conversation with Ulrich Dempfle, co-founder and CEO of CAROL Bike—a revolutionary device designed to transform the way we think about exercise and its impact on physiology. If you’ve ever believed that fitness required hours in the gym, this episode will challenge everything you thought you knew. Discover how two 20-second sprints can unlock powerful physiological benefits—triggering improvements in cardiovascular health, muscular strength, metabolic function, and more, in just 5 minutes a day.
Ulrich Dempfle
Ulrich Dempfle isn't just building a better bike—he's delivering a new model for how we approach fitness at a physiological level. In this episode, Ulrich and Christian explore how the CAROL Bike, using a scientifically validated protocol called REHIT (Reduced Exertion High-Intensity Interval Training), can deliver double the health benefits of a 45-minute run in under 10 minutes. But this isn’t just about saving time—it’s about activating the body's innate systems in the most efficient way possible.
Unlike traditional cardio machines, CAROL is powered by AI that customizes resistance in real-time, measuring your acceleration, effort, and fatigue to optimize every second of output. This precision unlocks a fight-or-flight response that rapidly depletes glycogen stores, triggering a cascade of molecular signaling, including AMPK and PGC-1α—known regulators of mitochondrial function and cellular energy. According to Ulrich, the short bursts of maximum intensity do more than burn calories—they reset the body’s metabolic machinery, improving VO₂ max, insulin sensitivity, blood pressure, and even leg strength.
What makes CAROL uniquely powerful is its ability to make lab-grade training protocols accessible to anyone—no lab technician required. Users see on average a 12% increase in VO₂ max, a 62% improvement in metabolic markers, and up to a 15% increase in lower-body strength—all within six to eight weeks. This kind of physiological shift typically requires intense, time-consuming training. CAROL condenses it into a workout that fits into a coffee break.
As Christian points out, CAROL isn’t simply a bike—it’s a physiological activation device. And that insight perfectly aligns with the core principle behind STEMREGEN: support the body's innate repair system by activating it through the right signals. Whether you're optimizing your energy, strengthening your cardiovascular system, or supporting your repair potential with STEMREGEN, technologies like CAROL offer a powerful path to better health, built on science and intention.
